RN Labs

RN LABS – Cal-D-Glucarate


A starting material for use in extemporaneous compounding only






Out of stock


  • Calcium-D-glucarate is the calcium salt of D-glucaric acid, a substance produced naturally in small amounts by mammals, including humans
  • Calcium-D-glucarate demonstrates detoxification properties supporting the excretion of potentially toxic compounds
    • Phase II detoxification facilitates excretion of chemical carcinogens, steroid hormones, and other lipid-soluble toxins via conjugation with glucuronic acid in the liver (glucuronidation), allowing water soluble excretion into the intestinal lumen
    • Calcium-D-glucarate has been shown to inhibit beta-glucuronidase, an enzyme produced by colonic microflora, capable of deconjugating bound toxins, making it possible for them to be reabsorbed rather than excreted
    • Elevated beta-glucuronidase activity has been associated with an increased risk for various cancers, particularly hormone-dependent cancers such as breast, prostate, and colon cancers (potentially due to accumulation of excess hormones and toxins)
    • Calcium-D-glucarate’s inhibition of betaglucuronidase activity allows the body to successfully excrete excess hormones (such as oestrogens) before they can be reabsorbed, reactivated and recirculated within the body
  • Vegan friendly
  • Does not contain wheat, gluten, dairy, lactose, egg, yeast, soy, artificial colours, artificial sweeteners, artificial flavours, synthetic preservatives, stearate lubricants

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